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Sodium oxybate: concomitant administration of codeine and sodium oxybate could cause increased CNS depression and/or respiratory depression and/or hypotension.
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Recommend patients not to regulate the dose of TYLENOL® with Codeine without consulting a medical professional or other Health care Skilled.
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Codeine, specifically in combination with other analgesics which include Paracetamol, has become shown for being effective in acute nociceptive pain.
You will find a relationship between growing codeine plasma concentration and increasing frequency of dose-associated opioid adverse reactions including nausea, vomiting, CNS effects, and respiratory depression.